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Thursday, November 14, 2019

CB Insights - Digital Health 150: The Digital Health Startups Redefining The Healthcare Industry

I have been trying to follow all the news from CB Insights: Technology Market Intelligence. They have extremely rich information on digital health. Here is a sample or intro:
https://www.cbinsights.com/research/

The most promising 150 private digital health startups working to transform the healthcare industry with new models of primary care to emerging tech solutions for providers.

CB Insights’ first ever annual cohort of Digital Health 150 startups is a list of 150 of the most promising private companies creating innovative products and services in the $5T+ healthcare industry, according to CB Insights’ Industry Analyst Consensus.
Our research team selected the 150 startups from a pool of 5K+ companies based on several factors, including patent activity, investor profile, news sentiment analysis, proprietary Mosaic scores, market potential, partnerships, competitive landscape, team strength, and tech novelty.
For the purposes of this report, digital health is defined as companies in the healthcare space that use technology/software as a key differentiator from their competition. This includes everything from disease diagnostics to tech-driven health insurance platforms to AI tools for drug discovery, and more.
Startups are categorized by their main focus areas. Categories in the market map below are not mutually exclusive.
Please click to enlarge.

Table of contents

150 startups in different stages of R&D

The Digital Health 150 companies span a wide spectrum of categories that involve all three key stakeholder groups for the healthcare industry — providers, payers, and patients.
These companies range from emerging startups to established unicorns (companies with $1B+ valuations). The selected companies represent a mix of startups at different stages of funding and product commercialization.

For example, China-based We Doctor has a valuation of $5.5B and provides primary care services that leverage its tech platforms and provider network.
In contrast, RDMD is an early-stage company specializing in drug discovery efforts for rare diseases. The company plans to aggregate data to help develop treatments for a range of conditions.
A total of 17 companies on the list are unicorns (private companies valued at $1B+). Of these, 12 companies are US-based, 3 are based in China, 1 is based in France, and 1 is based in the UK.
2019 Digital Health 150 Unicorn Startups
Company Category Country
We Doctor Providers: Primary Care China
GRAIL Genomics United States
Oscar Health Insurance & Benefits United States
Tempus Drug R&D: Real-World Evidence United States
GoodRx Pharma Supply Chain United States
23andMe Genomics United States
Babylon Health Providers: Primary Care (Virtual-Only) United Kingdom
Devoted Health Insurance & Benefits United States
HeartFlow Diagnostics: Imaging United States
Proteus Digital Health Digital Therapeutics United States
Butterfly Network Diagnostics: Imaging United States
Doctolib Providers: Primary Care (Virtual-Only) France
Hims Pharma Supply Chain United States
Calm Consumer Health & Wellness United States
LinkDoc Technology Drug R&D: Clinical Trials China
One Medical Group Providers: Primary Care United States
Tencent Trusted Doctors Providers: Primary Care China

Most well-funded companies

The most well-funded companies on the Digital Health 150 list span a broad range of categories. The top-funded company is genomics startup GRAIL, followed by insurance tech player Oscar Health and then China-based We Doctor.

Startups outside the United States

Of the 150 selected digital health startups, 116 are headquartered in the US. Those based outside the US include 17 from Asia, 16 from Europe, and 1 from Canada.

After the US, China is the second most-represented country on this list, with 7 of the selected companies, and Israel is third with 4 companies.

Most active investors

Over 850 unique investors have funded this year’s Digital Health 150 cohort, including corporations, CVCs, VC firms, and angel investors.
Below, we highlight the top 10 most active investors among the companies selected.
Investor Number of deals
F-Prime Capital 31
New Enterprise Associates 30
Google Ventures 29
Venrock 28
Founders Fund 27
Khosla Ventures 27
GE Ventures 22
Social Capital 20
.406 Ventures 19
Andreessen Horowitz 18

Track all the Digital Health 150 Startups in this brief and many more on our platform

The 150 private digital health startups working to recreate how healthcare is delivered. Look for The Digital Health 150 in the Collections tab.
Collections is the first collaborative work management solution purpose-built for corporate growth teams responsible for managing build, buy, or partner decisions.

Themes & trends

Across our 150 selected companies, we identified key themes and trends that highlight their efforts to transform the healthcare industry.
Below, we discuss a selection of these trends across different categories.

Artificial intelligence

Many companies on our list are leveraging AI and machine learning to help develop their respective software platforms.
From consumer health companies to imaging & diagnostics startups, AI is at the forefront of their products and services.
One example here is pathology — an area that AI has begun to transform. For instance, startups such as PathAI and PAIGE.AI are using AI to help speed up patient diagnosis.

Source: PAIGE.AI
AI is also being leveraged through drug discovery & development — accelerating the identification of new targets and therapeutic candidates.
An example here is OWKIN, a startup that develops algorithms to help interpret disease-related data and predict treatment outcomes.

Women’s health

As investments to women’s health startups have increased, we’ve seen startups targeting everything from egg freezing services to emerging tech for managing menopause.
In particular, fertility has gained traction as one of the main area of interest for women.
Startups such as Ava Science (fertility tracking device) and Carrot Fertility (fertility supplemental insurance) are providing novel services that aim to boost accessibility and convenience.
Virtual care clinics such as Maven Clinic are also helping women gain better access to providers that cater specifically to women’s health needs and concerns.

Source: Maven Clinic
Maven raised a $27M Series B round in September 2018 with participating investors including Sequoia Capital and Oak HC/FT Partners, among others.

Senior care

The growing size of the aging population is creating an increased demand for tech that aims to improve their health management.
This includes services targeted at both home care solutions and care coordination between providers.
One example here is ClearCare — a home care platform that aims to facilitate everything from administrative tasks to tracking patient hospitalizations.

Source: ClearCare

Social determinants of health

Population health has been generating a lot of buzz in healthcare. In particular, there’s a growing emphasis on leveraging social determinants of health (SDoH) to generate better health outcomes.
An example here is Unite Us, a New York-based startup working to build care networks that integrate SDoH into how healthcare is delivered.

Source: Unite Us
Its approach is to provide care coordination software that can handle external referrals and track patient outcomes, helping to connect healthcare with social services.

Value-based care

As more healthcare stakeholders look to collaboration to spur innovation in the industry, value-based care has come to the forefront.
In particular, payers and providers have established new care coordination networks to help reduce overall healthcare costs — with the goal of delivering care that provides better value to patients.
An example here is Vim, which provides patients with access to both payers and providers to make it easier to find appropriate care options.

Source: Vim
Vim raised a $24M Series B round in September, with participating investors including Optum Ventures, Premera Blue Cross, and Sequoia Capital, among others.

Concierge medicine

Concierge medicine startups, such as One Medical or Parsley Health, use a membership model to help offer patients an elevated healthcare services experience.
The approach aims to offer faster health visits with providers and more predictable associated costs.

Source: Galileo Health
Recently, Galileo Health — started by the founder of One Medical — launched an app-based concierge medicine platform geared towards providing a comprehensive level of care, including for chronic disease management.
It raised funding from Oak HC/FT Partners in May.

Telehealth

Telehealth services have expanded in recent years to become more differentiated.
Primary care platforms such as Ada Health and 98point6 are helping patients access more tailored care from their smartphones.
For instance, 98point6 offers a subscription on-demand telemedicine platform — touting 24/7 access to board-certified physicians — that’s delivered via a mobile app.

Source: 98point6
The startup raised a $50M Series C in October 2018 from Goldman Sachs and Frazier Healthcare Partners.
Another example is Talkspace, which offers psychotherapy services delivered virtually. It has raised $109M in total disclosed funding from investors including Compound, Norwest Venture Partners, Spark Capital, and SoftBank, among others.
Other companies in this category use remote monitoring technology to supplement virtual care services.

Table of the Digital Health 150 companies

2019 Digital Health 150 Companies
Company Category
Ava Science Consumer Health & Wellness
Calm Consumer Health & Wellness
CarePredict Consumer Health & Wellness
Ciitizen Consumer Health & Wellness
Dreem Consumer Health & Wellness
Headspace Consumer Health & Wellness
higi Consumer Health & Wellness
Oura Health Consumer Health & Wellness
TytoCare Consumer Health & Wellness
Aidoc Medical Diagnostics: Imaging
Arterys Diagnostics: Imaging
Butterfly Network Diagnostics: Imaging
eXo Imaging Diagnostics: Imaging
HeartFlow Diagnostics: Imaging
icometrix Diagnostics: Imaging
IDx Diagnostics: Imaging
Lifetrack Medical Systems Diagnostics: Imaging
Lunit Diagnostics: Imaging
Niramai Diagnostics: Imaging
Viz.ai Diagnostics: Imaging
VoxelCloud Diagnostics: Imaging
Zebra Medical Vision Diagnostics: Imaging
Athelas Diagnostics: Other Diagnostics
Cue Health Diagnostics: Other Diagnostics
Healthy.io Diagnostics: Other Diagnostics
Letsgetchecked Diagnostics: Other Diagnostics
Deep Lens Diagnostics: Pathology
PAIGE.AI Diagnostics: Pathology
PathAI Diagnostics: Pathology
Proscia Diagnostics: Pathology
Akili Interactive Labs Digital Therapeutics
Biofourmis Digital Therapeutics
Cara Care Digital Therapeutics
Click Therapeutics Digital Therapeutics
CureApp Digital Therapeutics
Glooko Digital Therapeutics
Kaia Health Digital Therapeutics
Lark Health Digital Therapeutics
Neurotrack Technologies Digital Therapeutics
Noom Digital Therapeutics
Omada Health Digital Therapeutics
Pear Therapeutics Digital Therapeutics
Pivot Digital Therapeutics
Proteus Digital Health Digital Therapeutics
SWORD Health Digital Therapeutics
Vida Health Digital Therapeutics
Virta Health Digital Therapeutics
Vivante Health Digital Therapeutics
AiCure Drug R&D: Clinical Trials
Emulate Drug R&D: Clinical Trials
LinkDoc Technology Drug R&D: Clinical Trials
Teckro Drug R&D: Clinical Trials
Atomwise Drug R&D: Drug Discovery & Development
Benchling Drug R&D: Drug Discovery & Development
Insitro Drug R&D: Drug Discovery & Development
OWKIN Drug R&D: Drug Discovery & Development
RDMD Drug R&D: Drug Discovery & Development
Recursion Pharmaceuticals Drug R&D: Drug Discovery & Development
Vineti Drug R&D: Drug Discovery & Development
Aetion Drug R&D: Real-World Evidence
Evidation Health Drug R&D: Real-World Evidence
GNS Healthcare Drug R&D: Real-World Evidence
Medbanks Network Technology Drug R&D: Real-World Evidence
Syapse Drug R&D: Real-World Evidence
Tempus Drug R&D: Real-World Evidence
TriNetX Drug R&D: Real-World Evidence
Verana Health Drug R&D: Real-World Evidence
23andMe Genomics
Color Genomics Genomics
Freenome Genomics
Genome Medical Genomics
GRAIL Genomics
Luna DNA Genomics
Nebula Genomics Genomics
Sophia Genetics Genomics
Viome Genomics
Accolade Insurance & Benefits
Alan Insurance & Benefits
Beam Dental Insurance & Benefits
Bend Financial Insurance & Benefits
Bright Health Insurance & Benefits
Carrot Fertility Insurance & Benefits
Cedar Insurance & Benefits
Collective Health Insurance & Benefits
Devoted Health Insurance & Benefits
Grand Rounds Insurance & Benefits
LEAGUE Insurance & Benefits
Modern Health Insurance & Benefits
Nomad Health Insurance & Benefits
Oscar Health Insurance & Benefits
Stride Health Insurance & Benefits
GoodRx Pharma Supply Chain
Hims Pharma Supply Chain
Nurx Pharma Supply Chain
Pill Club Pharma Supply Chain
Ro Pharma Supply Chain
TruePill Pharma Supply Chain
ClearCare Providers: Administrative Tools
ClearDATA Providers: Administrative Tools
HealthVerity Providers: Administrative Tools
Human API Providers: Administrative Tools
Jvion Providers: Administrative Tools
Kyruus Providers: Administrative Tools
Notable Providers: Administrative Tools
Olive Providers: Administrative Tools
Protenus Providers: Administrative Tools
Redox Providers: Administrative Tools
Solv Health Providers: Administrative Tools
SYNYI.AI Providers: Administrative Tools
Weimai Providers: Administrative Tools
DocPlanner Providers: Clinical Tools
Gauss Surgical Providers: Clinical Tools
KenSci Providers: Clinical Tools
MDClone Providers: Clinical Tools
MORE Health Providers: Clinical Tools
Oncology Analytics Providers: Clinical Tools
PatientPing Providers: Clinical Tools
Quartet Health Providers: Clinical Tools
Solera Providers: Clinical Tools
Suki Providers: Clinical Tools
Unite Us Providers: Clinical Tools
Welkin Health Providers: Clinical Tools
Vim Providers: Clinical Tools
Cityblock Health Providers: Primary Care
Iora Health Providers: Primary Care
One Medical Providers: Primary Care
Parsley Health Providers: Primary Care
Tencent Trusted Doctors Providers: Primary Care
We Doctor Providers: Primary Care
Galileo Health Providers: Primary Care (Virtual-Only)
Halodoc Providers: Primary Care (Virtual-Only)
98point6 Providers: Primary Care (Virtual-Only)
Ada Health Providers: Primary Care (Virtual-Only)
American Well Providers: Primary Care (Virtual-Only)
Babylon Health Providers: Primary Care (Virtual-Only)
Buoy Health Providers: Primary Care (Virtual-Only)
Doctolib Providers: Primary Care (Virtual-Only)
Doctor On Demand Providers: Primary Care (Virtual-Only)
K Health Providers: Primary Care (Virtual-Only)
Kry Providers: Primary Care (Virtual-Only)
Lyra Health Providers: Primary Care (Virtual-Only)
MDLIVE Providers: Primary Care (Virtual-Only)
Zava Providers: Primary Care (Virtual-Only)
Cricket Health Providers: Specialty Care
DispatchHealth Providers: Specialty Care
Kindbody Providers: Specialty Care
Xiaolu Yiguan Providers: Specialty Care
AbleTo Providers: Specialty Care (Virtual-Only)
Maven Clinic Providers: Specialty Care (Virtual-Only)
Talkspace Providers: Specialty Care (Virtual-Only)


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